Sodium Copper Chlorophyllin (Phytochromatic MD™ Complex) Shown Effective in Improving Photodamaged Skin
SAN DIEGO, CA – April 7, 2015 – MDRejuvena, Inc., announced the publication of the first study evaluating the use of topical sodium copper chlorophyllin complex in women with photodamaged facial skin. The study, published in the April issue of the Journal of Drugs and Dermatology, demonstrated that a topical formulation containing a liposomal dispersion of sodium copper chlorophyllin (Phytochromatic MD™ Complex) was clinically effective and well tolerated for the treatment of mild to moderate photodamage and solar lentigenes when used for an 8 week period.
Chronic exposure to the sun causes the skin to prematurely age. Photodamaged skin is characterized by progressive damage to the dermal extracellular matrix with loss of collagen and degradation of elastin. Clinical manifestations of such photodamaged skin include wrinkles, skin laxity, coarseness and irregular pigmentation.
"These results are very encouraging," stated David B. Vasily, MD, of Aesthetica Cosmetic & Laser Center, Bethlehem, PA. "This complex of copper chlorophyllin produced numerous clinical improvements in women with photodamaged skin. Practitioners now have a new, natural-based option for treating patients with photoaged skin."
The single-center pilot study, titled, “Assessment of the Safety and Efficacy of Topical Copper Chlorophyllin in Women with Photodamaged Facial Skin,” included ten female subjects with mild to moderate fine lines and wrinkles in the periocular areas and facial solar lentigenes. Each subject applied the topical gel containing chlorophyllin complex salts (0.066%) to the periocular areas, cheeks and nose every morning and evening over a course of 8 weeks. All clinical efficacy parameters showed statistically significant improvements over baseline at week 8. These parameters included overall photodamaged skin appearance, fine lines in periocular area, coarse wrinkles in periocular area, visual roughness, tactile roughness, skin radiance, pore size and dyschromia. Significant improvements were also seen in skin elasticity and size and color of sun spots.
David F. Hale, Executive Chairman and Acting Chief Executive Officer of MDRejuvena, stated, “We are very excited about these results and the potential for our Rejuvaphyl line of skin health products to significantly benefit women who have photodamaged skin. We believe that our Rejuvaphyl products will reduce the multiple manifestations of photodamaged skin such as irregular pigmentation, lines, wrinkles, skin laxity and coarseness.”
Salts of copper chlorophyllin complex are semi-synthetic naturally-derived compounds with anti-inflammatory, antioxidant and wound healing activity that has not been previously tested in photodamaged skin. Phytochromatic MD Complex is the primary ingredient in the Rejuvaphyl line of skin care products from MDRejuvena.
MDRejuvena is a private company focused on the licensing, development and commercialization of products for skin health for the professional physician-dispensed market in the U.S. and internationally. Further information on the Company can be found at www.mdrejuvena.com or by calling 888-MDR-3003.
MDREJUVENA and REJUVAPHYL are trademarks of MDRejuvena, Inc.
PHYTOCHROMATIC MD is a trademark of CHL Industries, LLC