Sodium Copper Chlorophyllin (Phytochromatic MD™ Complex) Shown to Have Clinical Activity in Patients With Acne and Large Pores

SAN DIEGO, CA – July 7, 2015 – MDRejuvena, Inc., announced the publication of a pilot clinical study evaluating the use of topical copper chlorophyllin complex in subjects with facial acne and large pores. The study, published in the June issue of the Journal of Drugs and Dermatology, showed a topical formulation containing a liposomal dispersion of sodium copper chlorophyllin to have clinical activity and be well tolerated for the treatment of mild to moderate acne and large, visible pores when used for 3 weeks.


Acne vulgaris is one of the most common skin diseases treated by dermatologists. This chronic disease is estimated to affect 40 to 50 million people in the U.S. While acne is usually recognized as a disorder of adolescents, the prevalence of adult acne (particularly in females) has increased significantly in recent years. Topical administration is the most common means of delivering anti-acne medications and such treatments typically include retinoids, benzoyl peroxide, antibiotics and various combinations of those treatments.


“We are very pleased with the activity exhibited by copper chlorophyllin in this study,” stated David F. Hale, Executive Chairman and Acting Chief Executive Officer of MDRejuvena. “This finding will be very important as we develop our acne treatment regimen which we plan to introduce in 2016”.


The study, titled “Pilot Study of Topical Copper Chlorophyllin Complex in Subjects with Facial Acne and Large Pores,” included 10 subjects with mild to moderate acne and large, visible pores who applied a small amount of a topical gel containing a liposomal dispersion of sodium copper chlorophyllin complex (0.1%) twice daily over a course of 3 weeks. All clinical parameters showed statistically significant improvements over baseline at week 3. The greatest changes were seen in facial oiliness, facial pores and blotchiness. The study product was also well tolerated by the subjects. Typical reactions such as dryness, irritation and redness, which are often seen with other topical acne preparations, were not seen with the sodium copper chlorophyllin preparation. Additionally, the test product was highly rated in subject questionnaires.



Salts of copper chlorophyllin complex are naturally-derived compounds with antioxidant, anti-inflammatory and wound healing activity, which also exhibit antimicrobial activity against P. acnes. Sodium copper chlorophyllin has not been previously tested topically in the treatment of acne-prone skin with enlarged pores. Copper chlorophyllin in a liposomal complex, called Phytochromatic MD Complex, is the primary ingredient in the Rejuvaphyl™ line of skin care products from MDRejuvena.


About MDRejuvena


MDRejuvena is a private company focused on the licensing, development and commercialization of products for skin health for the professional physician-dispensed market in the U.S. and internationally. Further information on the Company can be found on or by calling 888-MDR-3003.


MDREJUVENA and REJUVAPHYL are trademarks of MDRejuvena, Inc.

PHYTOCHROMATIC MD is a trademark of CHL Industries, LLC